Three more trials are going on in China; two coordinated by Tinjian Universiy and a third one in Wuhan’s Union Hospital. We only have a preliminary report of the first two cases. Another trial is waiting for approval in Italy and two more trials are being prepared in Portugal and Brazil, all last three with WFOT’s help. We hope that last trials are approved and we soon get data enough to help our patients. WFOT will not publish preliminary protocols or data without permission from the trial’s coordinator unless it is required by health authorities. Meanwhile, we must follow STRICTLY the advises from these authorities.
UPDATE – 27/03/2020
Other trials have been accepted in hospitals of Romania and Turkey and are pending their ethic committees’ final approval.
UPDATE – 28/03/2020
Other trial promoted by NuovaFIO has already started in Poliambulanza Institute Hospital Foundation in Brescia after approval of its Ethic Committee. It also pending of registration in the web of Clinical Trials.
UPDATE – 06/04/2020
The University Hospital Santa Maria della Misericordia in Udine – Italy has done a pilot study under the approval of the hospital’s ethic committee. They obtained very positive results in 35 of the 36 patients treated, reducing the intubation rate from 15% to 3%. They have applied for approval from Spallanzani Institute in Rome to start a randomized clinical trial.
UPDATE – 10/04/2020
The University Hospital Santa Maria della Misericordia in Udine – Italy has got approval of its Ethic Committee to start a randomized clinical trial. Spallanzani Institute in Rome and AIFA (Italian Drug Agency) have declared themselves as not competent to approve the trial as ozone is not a drug. Several hospitals are sending applications to this hospital in order to join its clinical trial.